By Tamara Straus

On February 26, 2018, Maria Artunduaga had a eureka moment that medical entrepreneurs dream of. In the office of UCSF Professor Mehrdad Arjomandi, she was soliciting advice about a wearable prototype she had developed to monitor oxygen in patients with chronic obstructive pulmonary disease (COPD). Dr. Arjomandi—a clinical professor and foremost expert on COPD—was telling her about an air trapping investigation he had been doing for over a decade. He was bemoaning the enormous time and expense involved in testing patients with COPD, the third leading cause of U.S. deaths.